中国组织工程研究

中国组织工程研究 ›› 2018, Vol. 22 ›› Issue (35): 5631-5636.doi: 10.3969/j.issn.2095-4344.1008

• 骨与关节生物力学 bone and joint biomechanics • 上一篇    下一篇

滚压载荷下有无缺损关节软骨的力学性能研究

李志强1，2，高丽兰1，2，司雲朋1，2，张春秋1，2   

  1. 1天津理工大学天津市先进机电系统设计与智能控制重点实验室，天津市 300384；2机电工程国家级实验教学示范中心(天津理工大学)，天津市  300384
  • 出版日期:2018-12-18 发布日期:2018-12-18
  • 通讯作者: 通讯作者：高丽兰，博士，副教授，天津理工大学天津市先进机电系统设计与智能控制重点实验室，天津市300384；机电工程国家级实验教学示范中心(天津理工大学)，天津市 300384 通讯作者：张春秋，博士，教授，天津理工大学天津市先进机电系统设计与智能控制重点实验室，天津市300384；机电工程国家级实验教学示范中心(天津理工大学)，天津市 300384
  • 作者简介:李志强，男，1993年生，河北省张家口市人，汉族，天津理工大学在读硕士，主要从事生物力学方向的研究。
  • 基金资助:

    国家自然科学基金项目(11572222，11672208，11432016)

Mechanical properties of intact and defective articular cartilage under rolling load  

Li Zhiqiang1, 2, Gao Lilan1, 2, Si Yunpeng1, 2, Zhang Chunqiu1, 2   

  1. 1Tianjin Key Laboratory for Advanced Mechatronic System Design and Intelligent Control, School of Mechanical Engineering, Tianjin University of Technology, Tianjin 300384, China; 2National Demonstration Center for Experimental Mechanical and Electrical Engineering Education, Tianjin University of Technology, Tianjin 300384, China
  • Online:2018-12-18 Published:2018-12-18
  • Contact: Corresponding author: Gao Lilan. MD, Associate professor, Tianjin Key Laboratory for Advanced Mechatronic System Design and Intelligent Control, School of Mechanical Engineering, Tianjin University of Technology, Tianjin 300384, China; National Demonstration Center for Experimental Mechanical and Electrical Engineering Education, Tianjin University of Technology, Tianjin 300384, China Corresponding author: Zhang Chunqiu, MD, Professor, Tianjin Key Laboratory for Advanced Mechatronic System Design and Intelligent Control, School of Mechanical Engineering, Tianjin University of Technology, Tianjin 300384, China; National Demonstration Center for Experimental Mechanical and Electrical Engineering Education, Tianjin University of Technology, Tianjin 300384, China
  • About author:Li Zhiqiang, Master candidate, Tianjin Key Laboratory for Advanced Mechatronic System Design and Intelligent Control, School of Mechanical Engineering, Tianjin University of Technology, Tianjin 300384, China; National Demonstration Center for Experimental Mechanical and Electrical Engineering Education, Tianjin University of Technology, Tianjin 300384, China
  • Supported by:

    the National Natural Science Foundation of China, No. 11572222, 11672208 and 11432016

PDF

175

摘要：

文章快速阅读：



 
文题释义：
非接触数字相关技术：非接触式测量方法以前主要有光学式和气动式两种，研究为光学式图像采集系统，图像测量技术作为一种新兴的非接触测量方法有着独特的优越性，它通过把被测对象的图像作为检测和传递信息的手段，从图像中提取有用信息进而获得待测参数，研究通过图像采集点的坐标变化从而计算出受载前后软骨的应变。
应力集中：是指受力构件由于外界因素或自身因素导致几何形状、外形尺寸发生突变而引起局部范围内应力显著增大的现象，使物体产生疲劳裂纹，是工程评价材料可靠性跟安全性的重要指标。
 
摘要
背景：膝关节是人体运动的主要承重组织，也是临床上疾病的好发部位。滚压负载对膝关节软骨组织的生理、病理有较大影响，但目前对此研究较少。
目的：通过新的滚压装置在控制不同的滚压速率、压缩量，在滚压次数最大为150次的连续加载下研究完整与缺损软骨的力学性能。
方法：首先制备完整与缺损猪关节软骨试样，通过滚压装置控制不同的载荷条件。以非接触数字相关技术进行图像采集，观察滚压条件下完整及缺损软骨不同层区的应变情况。
结果与结论：滚压载荷下，不管是完整软骨还是缺损软骨，都是浅表层区应变最大，深层区最小，中间层位于二者之间。软骨缺损附近的各层应变较完整软骨更大。随着压缩量的增加，缺损软骨在连续滚压载荷下缺损附近的应变变化也较大。滚压速率越大，到达最大稳定的应变也越快。提示不同滚压速率、不同压缩量和缺损都会影响膝关节软骨组织的力学性能，也使得软骨不同层区的力学性能表现不同。软骨缺损导致滚压载荷下软骨组织的变形增大，这可能会进一步加重软骨的损伤。

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程
ORCID: 0000-0002-7953-5790(张春秋)

关键词: 膝关节软骨, 完整, 缺损, 滚压速率, 压缩量, 应变, 不同层区, 数字化骨科

Abstract:

BACKGROUND: Knee joint is the main load-bearing tissue during movement and it is also a predilection site for clinical disease. Rolling load makes a great influence on the physiology and pathology of the knee cartilage, but the relative studies are few.

OBJECTIVE: To explore the mechanical properties of intact and defective cartilage tissue under rolling load at different rolling velocities, different compression amounts, and maximum rolling times of 150.
METHODS: The intact and defective cartilage tissues from pig knee were prepared. Different loads were controlled using rolling device. The strains of different layers of the intact and defective cartilage tissues under rolling were studied.
RESULTS AND CONCLUSION: Under rolling load, the normal strains of superficial layers of both intact and defective cartilages were largest, followed by the middle layer, and the deep layer was smallest. The normal strain of each layer near the cartilage defect was greater than that of the intact cartilage. With the increase of compression, the normal strains of different layers of articular cartilage were increased, and the strain of defect cartilage near the defect area was also increases greatly. The faster the rolling rate, the faster the strain reached the maximum stability. In summary, the mechanical properties of different layers of cartilage are affected by rolling velocity, compression and defect. Cartilage defects lead to the increased deformation of the cartilage tissue under rolling loads, which may further aggravate cartilage damage.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Cartilage, Articular, Biomechanics, Tissue Engineering

中图分类号: